Pregnancy-associated plasma protein A (PAPP-A) for the early diagnosis of myocardial infarction: More doubts than certainties
نویسندگان
چکیده
منابع مشابه
Pregnancy-associated plasma protein-E (PAPP-E).
A full-length cDNA encoding a novel human protein was cloned from placenta cDNA. The corresponding 1542 amino acid protein sequence was termed 'pregnancy-associated plasma protein-E' (PAPP-E) as it shows a 62% homology to the human pregnancy-associated plasma protein-A (PAPP-A) that is a diagnostic marker for trisomies, especially Down syndrome. The conserved domain structure contains five moti...
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REPLY: In their letter to the editor, in this issue of the American Journal of Physiology-Lung Cellular and Molecular Physiology, Caruso and colleagues (3) reprise longstanding arguments that the tobacco industry uses to cast doubt on evidence linking smoking with disease (7) to question our conclusion that e-cigarettes pose important potential pulmonary risks (4). They argue that we have syste...
متن کاملMolecular distinction of circulating pregnancy-associated plasma protein A in myocardial infarction and pregnancy.
BACKGROUND In the blood of pregnant women, pregnancy-associated plasma protein A (PAPP-A) is present as a covalent complex with the proform of eosinophil major basic protein (proMBP). Recently, increased serum concentrations of PAPP-A have been found in acute coronary syndromes (ACS). The aim of this study was to investigate whether the circulating PAPP-A in ACS is the same as that in pregnancy...
متن کاملPregnancy-associated plasma protein-E (PAPP-E)1
A full-length cDNA encoding a novel human protein was cloned from placenta cDNA. The corresponding 1542 amino acid protein sequence was termed `pregnancy-associated plasma protein-E' (PAPP-E) as it shows a 62% homology to the human pregnancy-associated plasma protein-A (PAPP-A) that is a diagnostic marker for trisomies, especially Down syndrome. The conserved domain structure contains five moti...
متن کاملComparison of pregnancy-associated plasma protein-A, troponin and creatine kinase-MB levels in acute coronary syndrome
Background: Early diagnosis and proper treatment of patient with acute coronary syndrome (ACS) and ischemic heart disease are important in determining prognosis, preventing adverse effects, and may even save lives. In this study, the level of pregnancy-associated plasma protein-A (PAPP-A) in ACS patients was compared with the control group, in addition to cardiac Troponin (cTn) and creatine kin...
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ژورنال
عنوان ژورنال: Indian Heart Journal
سال: 2012
ISSN: 0019-4832
DOI: 10.1016/j.ihj.2012.10.005